Increased Expression of IP-10, IL-8, MCP-1, and MCP-3 in Ulcerative Colitis
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چکیده
منابع مشابه
Differential involvement of phosphoinositide 3-kinase/Akt in human RPE MCP-1 and IL-8 expression.
PURPOSE To investigate the role of the phosphatidylinositol 3-kinase (PI3K) pathway and the signal mediator AP-1 in monocyte chemotactic protein (MCP)-1 and interleukin (IL)-8 gene expression in human retinal pigment epithelial (hRPE) cells. METHODS hRPE cells were stimulated with IL-1beta and TNF-alpha and by coculturing with monocytes in the presence or absence of a series of kinase inhibit...
متن کاملبررسی ارتباط سطح سایتوکاین های 1β-IL ، α-TNF ، 10-IP ، MCP درترشحات اندومتریال با میزان موفقیت باروری آزمایشگاهی
Introduction & Objective: Cytokines produced by fetal and uterine mucus are responsible for regulating interactions between mother and fetus that improve uterus receptivity and leads to higher success rate of in vitro fertilization (IVF). The aim of the present study was to evaluate the relationship between levels of some cytokines (IL-1?, TNF-?, IP-10, and MCP) in endo-metrial secretions with ...
متن کاملNon-infected preterm parturition is related to increased concentrations of IL-6, IL-8 and MCP-1 in human cervix
BACKGROUND Human cervical ripening is an inflammatory process. In labour at term the mRNA-levels and protein concentrations for interleukin-6 (IL-6) and IL-8 in cervix significantly increase. The aim of this study was to investigate if there are differences in the inflammatory process of preterm and term cervical ripening. METHODS Cervical biopsies from 50 singleton pregnant women without cli...
متن کاملMolecular Regulation of IL-13 and MCP-1 Expression in Human Mast Cells by IL-1β
Mast cells play pivotal roles in IgE-mediated airway inflammation, expressing interleukin13 (IL-13) and monocyte chemoattracant protein-1 (MCP-1), which in turn regulate IgE synthesis and/or inflammatory cell recruitment. The molecular effects of interleukin-1 beta (IL-1β) on cytokine expression by human mast cells have not been studied well. In this report, we provide evidence that human mast ...
متن کاملTNF-induced IL-8 and MCP-1 production in the eosinophilic cell line, EOL-1
The role of eosinophils in inflammation and their mode of activation is not well understood. Eosinophil accumulation and subsequent expression of cytokines at the site of inflammation may play a role in exacerbation of inflammatory responses. In the present study, we have examined the role of TNF-alpha in eosinophil activation and chemokine production using a human leukaemic eosinophil cell lin...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 1999
ISSN: 0002-9440
DOI: 10.1016/s0002-9440(10)65128-0